Grey matter unveiling PSG COLLEGE OF TECHNOLOGY STUDENTS UNION STUDENTS UNION presents DEPARTMENT OF BIOTECHNOLOGY GREY MATTER GREY MATTER UNVEILING UNVEILING -a Sci-Tech Mania GREY MATTER UNVEILING Selected Teams: alpha : beta : gamma : delta : epsilon : zeta : Prelims Field of interest First Round MICROBIOLOGY BIOCHEMISTRY MOLECULAR BIOLOGY IMMUNOLOGY GENETICS PHYSIOLOGY FIELDS Microbiology Who was the first to speculate the possibility of a ‘magic bullet’ that would destroy a pathogen without harming the host? Somatic cells divide by mitosis and Reproductive cells by meiosis. Then how do Bacterial cells divide? What are the stains used for Electron Microscopy? By saying ‘little staff’, what are you actually referring to? Name the important component found in Bacterial Endospores? Psychrotroph is an organism that grows best at 0˚C. True or False. Identify the microbe which caused the global outbreak of fever, sore throat, cough, headache and respiratory illness in 2009. media for the growth of anaerobes. (a) blood agar (b)Tryptic soy media (c) LB media Which are the largest living bacteria? Compare and contrast sterilization and sanitation. Biochemistry What is the difference between Apoenzyme and Holoenzyme? What is the amount of energy released during the hydrolysis of an ATP to ADP? To which amino acid does the letter ‘W’ correspond to? What do you infer from a polyprotein? Among the following which is a supersecondary structure? (a) alpha helix (b) beta sheet (c) gamma barrel (d) beta-alpha-beta motif Cyclins are proteins that (a) regulate ability of cells to invade tissue (b) regulate progression from one stage of cell division to another (c) regulate apoptosis of damaged cells (d) none of the above. Why humans cannot use cellulose as a carbon source? Why are cows able to digest cellulose? Which theory does this graphical representation depict? Phenylketonuria is a _______ disorder. Autosomal dominant Autosomal recessive X linked dominant X linked recessive The presence of which hormone is looked for pregnancy test? Molecular Biology What is the difference between positive and negative supercoiling? What is meant by the Shine Dalgarno sequence? Distinguish between an ORF and a gene. What is star activity? Why does the incorporation of a dideoxynucleotide stop strand elongation dead in its tracks? Distinguish between Euchromatin and Heterochromatin. What are IS elements? I am a region with very short repeated sequences. Microsatellites and Minisatellites are included in me. Who am I? What do you infer from selfish DNA? Identify this complex. Immunology 1.What does TSTA stand for? Identify this instrument that is used to measure the concentration of Ig A .G and M. 2.The exposure of an antigen to the human body results in primary response. The second exposure produces an intensified response called __________ response. 3.What are the five classes of immunoglobulins? How are the haptens related to allergic response? 6 years old Susie is found playing in a patch of poison ivy. She did not develop any symptoms.5 months later, on a trip, she comes in contact with poison ivy. This time she develops a severe contact dermatitis? Why not first time? Why now? T cells mature in the______________ a)thyroid gland b)bone marrow c)lymph nodes d)none of these Class switching pertains to a)paratopes b)epitopes c)MHC molecules d)light Ig chains e)heavy Ig chains Macrophages are classified as a)APC b)lymphocytes c)cDs d)specific effector cells e)regulatory cells A term that denotes the number of antigen combining sites on an immunoglobulin molecule? Genetics How many base pairs does a centimorgan equal to? Which organism has the largest genome? What do you infer from genetic anticipation? A polymer is made up of 75% G and 25% U. Among the amino acids in the polypeptide chain,what is the expected frequency of Trp? Of Val? And of Phe? ( Hint : the triplet codon for Trp is UGG, Val is GUU and GUG and that of Phe is UUU). 5 What Genetic Interaction does this flower explain? What does chromosome interference refer to? A chemical say carbolic acid(phenol) destroys proteins but not nucleic acids. A strong alkali such as sodium hydroxide destroys both nucleic acids and proteins. In the experiment with Streptococcus pneumonia, what result could be expected if the S-strain extract had been treated with phenol and also with NaOH? Is it possible for a gene with a mutation in the coding region to encode a polypepeptide with the same amino acid sequence as the nonmutant gene? How are the restriction enzymes named? BamHI, EcoRI,HindIII and TaqI. Name the ‘disease gene’ or the ‘genetic marker’ for breast cancer. Physiology Expand MAOI. What is retinitis pigmentosa? What are tranquilizers? Expand LDL. What is paradoxical sleep? a)SEM alone b)REM alone c) both SEM AND REM d)neither SEM NOR REM The ____________ is the site of action potential initiation in most neurons because it has the lowest threshold. Which of the following activities is not carried out by every cell in the body? a)obtaining nutrient and o2 b)performing chemical reaction to acquire energy for the cell’s use c)eliminating waste d)controlling to a large extent exchange of materials between the cell and its external environment e)reproducing What is cytopathic effect? What are Merkel’s discs and Meisseners’s corpuscles? Mention the tiniest bones of the human body. Video Round Second Round Nano Robots What is the abbreviation of Nubots? Which is the main element used to construct nanorobots? What for MRN nanorobots used? Dyslexia In which film was this disorder picturised? (mock question) Who is the director of Taare Zameen Par? Name a few symptoms of this disorder. What are the types of Dyslexia? Paa Which genetic disorder is this film based upon? How is this disorder caused? Mention a few symptoms. Immune Response What is cyclosporine? How did thymus get its name? How many lymph nodes are present in the human body? Pronuclear Microinjection Which is the first genetically modified animal to be sold as pet? What do you mean by cisgenic plants? Name the leading U.S based multinational agricultural biotechnology corporation. Myocardial Infarction Why is aspirin given as first aid? Name any five risk factors for myocardial infarction. Which is good for health? LDL or HDL? Motility The movement of cells along a rigidity gradient is called _____________________. How does Eukaryotic flagella differ from that of prokaryotes? Name the protein present in bacterial flagella. Picture Revealing Third Round 6 2 3 1 9 5 8 4 7 BLOCK 1 He was born in Montclair, N.J. on May 23, 1925. BLOCK 2 American molecular biologist known for his work in genetics, artificial intelligence, and space exploration. BLOCK 3 In the year 1958, he was also elected to the National Academy of Sciences (USA). BLOCK 4 In 1978, he became the president of Rockefeller University. BLOCK 5 He began medical studies at Columbia's College of Physicians and Surgeons. BLOCK 6 In 1960s, he collaborated with Edward Feigenbaum in Stanford's computer science department to develop DENDRAL. BLOCK 7 He continues his research activities there in the field of interactions of gene functionality and mutagenesis in bacteria. BLOCK 8 He was just 33 years old when he won the 1958 Nobel Prize in Physiology or Medicine for discovering that bacteria can mate and exchange genes. BLOCK 9 He shared the prize with Edward L. Tatum and George Beadle who won for their work with genetics. 4 2 3 6 9 8 7 1 5 BLOCK 1 He discovered – in co-operation with Erwin Popper – the infectious character of Poliomyelitis and isolated the poliovirus. BLOCK 2 He was awarded Nobel Prize in Physiology or Medicine (1930). BLOCK 3 Major area of study- immunology BLOCK 4 In the field of bacteriology he and Clara Nigg succeeded in 1930-1932 in culturing Rickettsia prowazekii, the causative agent of typhus. BLOCK 5 Born in Vienna on June 14, 1868. (1868-06-14)Died on June 26, 1943 in New York City. BLOCK 6 Austrian-american biologist and pathologist. BLOCK 7 In 1909, he categorized the modern system for human bloods into A, B, AB, and O groups. BLOCK 8 He revealed new information regarding the immunology of syphilis and named the immunological factors haptens. BLOCK 9 With Alexander S. Wiener, he identified the Rh factor in 1937. 2 4 5 3 6 9 8 7 1 BLOCK1 Between 1988 and 1992, he was associated with the National Institutes of Health, helping to establish the Human Genome Project.   104 BLOCK 2 He is an American molecular biologist. BLOCK 3 He was awarded Nobel Prize for Physiology or Medicine (1962) and Copley Medal (1993). BLOCK 4 He also served as the advisor of Allen Institute for Brain Sciences. BLOCK 5 He was born on April 6, 1928. BLOCK 6 He authored the controversial book, ‘Avoid Boring People: Lessons from a Life in Science’, describes his academic colleagues as "dinosaurs," "deadbeats," "fossils," "has-beens," "mediocre," and "vapid. BLOCK 7 His famous quote, “Biology has atleast 50 more interesting years”. BLOCK 8 Between 1953 and 1955, he was at the California Institute of Technology as Senior Research Fellow in Biology. He collaborated with Alexander Rich in X-ray diffraction studies of RNA. BLOCK 9 He was the author of the textbook “The Molecular Biology of the Gene (1965)”. 1 2 4 5 3 6 9 8 7 113 BLOCK 1 The crater on the Moon is named after him.   BLOCK 2 He was awarded the Nobel Prize in Physiology or Medicine for his tuberculosis findings in 1905. BLOCK 3 He is considered as one of the founders of bacteriology along with Louis Pasteur. BLOCK 4 The son of a mining engineer, he astounded his parents at the age of five by telling them that he had, with the aid of the newspapers, taught himself to read. BLOCK 5 He was born on December 11,1843 and expired on May 27, 1910. BLOCK 6 He was a German physician. BLOCK 7 He became famous for isolating Bacillus anthracis (1877), the Tuberculosis bacillus (1882) and the Vibrio cholera (1883) BLOCK 8 He is known for his four assertions designed to establish a causal relationship between a causative microbe and a disease. BLOCK 9 He improved staining and purification techniques, and bacterial growth media, including agar plates . Rapid Fire Round Final Round SET 1 SET 1 SET 1 SET 2 SET 2 SET 2 SET 3 SET 3 SET 3 SET 4 SET 4 SET 4 Thank You
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Grey Matter Unveiling

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Grey matter unveiling PSG COLLEGE OF TECHNOLOGY STUDENTS UNION STUDENTS UNION presents DEPARTMENT OF BIOTECHNOLOGY GREY MATTER GREY MATTER UNVEILING UNVEILING -a Sci-Tech Mania GREY MATTER UNVEILING Selected Teams: alpha : beta : gamma : delta : epsilon : zeta : Prelims Field of interest First Round MICROBIOLOGY BIOCHEMISTRY MOLECULAR BIOLOGY IMMUNOLOGY GENETICS PHYSIOLOGY FIELDS Microbiology Who was the first to speculate the possibility of a ‘magic bullet’ that would destroy a pathogen without harming the host? Somatic cells divide by mitosis and Reproductive cells by meiosis. Then how do Bacterial cells divide? What are the stains used for Electron Microscopy? By saying ‘little staff’, what are you actually referring to? Name the important component found in Bacterial Endospores? Psychrotroph is an organism that grows best at 0˚C. True or False. Identify the microbe which caused the global outbreak of fever, sore throat, cough, headache and respiratory illness in 2009. media for the growth of anaerobes. (a) blood agar (b)Tryptic soy media (c) LB media Which are the largest living bacteria? Compare and contrast sterilization and sanitation. Biochemistry What is the difference between Apoenzyme and Holoenzyme? What is the amount of energy released during the hydrolysis of an ATP to ADP? To which amino acid does the letter ‘W’ correspond to? What do you infer from a polyprotein? Among the following which is a supersecondary structure? (a) alpha helix (b) beta sheet (c) gamma barrel (d) beta-alpha-beta motif Cyclins are proteins that (a) regulate ability of cells to invade tissue (b) regulate progression from one stage of cell division to another (c) regulate apoptosis of damaged cells (d) none of the above. Why humans cannot use cellulose as a carbon source? Why are cows able to digest cellulose? Which theory does this graphical representation depict? Phenylketonuria is a _______ disorder. Autosomal dominant Autosomal recessive X linked dominant X linked recessive The presence of which hormone is looked for pregnancy test? Molecular Biology What is the difference between positive and negative supercoiling? What is meant by the Shine Dalgarno sequence? Distinguish between an ORF and a gene. What is star activity? Why does the incorporation of a dideoxynucleotide stop strand elongation dead in its tracks? Distinguish between Euchromatin and Heterochromatin. What are IS elements? I am a region with very short repeated sequences. Microsatellites and Minisatellites are included in me. Who am I? What do you infer from selfish DNA? Identify this complex. Immunology 1.What does TSTA stand for? Identify this instrument that is used to measure the concentration of Ig A .G and M. 2.The exposure of an antigen to the human body results in primary response. The second exposure produces an intensified response called __________ response. 3.What are the five classes of immunoglobulins? How are the haptens related to allergic response? 6 years old Susie is found playing in a patch of poison ivy. She did not develop any symptoms.5 months later, on a trip, she comes in contact with poison ivy. This time she develops a severe contact dermatitis? Why not first time? Why now? T cells mature in the______________ a)thyroid gland b)bone marrow c)lymph nodes d)none of these Class switching pertains to a)paratopes b)epitopes c)MHC molecules d)light Ig chains e)heavy Ig chains Macrophages are classified as a)APC b)lymphocytes c)cDs d)specific effector cells e)regulatory cells A term that denotes the number of antigen combining sites on an immunoglobulin molecule? Genetics How many base pairs does a centimorgan equal to? Which organism has the largest genome? What do you infer from genetic anticipation? A polymer is made up of 75% G and 25% U. Among the amino acids in the polypeptide chain,what is the expected frequency of Trp? Of Val? And of Phe? ( Hint : the triplet codon for Trp is UGG, Val is GUU and GUG and that of Phe is UUU). 5 What Genetic Interaction does this flower explain? What does chromosome interference refer to? A chemical say carbolic acid(phenol) destroys proteins but not nucleic acids. A strong alkali such as sodium hydroxide destroys both nucleic acids and proteins. In the experiment with Streptococcus pneumonia, what result could be expected if the S-strain extract had been treated with phenol and also with NaOH? Is it possible for a gene with a mutation in the coding region to encode a polypepeptide with the same amino acid sequence as the nonmutant gene? How are the restriction enzymes named? BamHI, EcoRI,HindIII and TaqI. Name the ‘disease gene’ or the ‘genetic marker’ for breast cancer. Physiology Expand MAOI. What is retinitis pigmentosa? What are tranquilizers? Expand LDL. What is paradoxical sleep? a)SEM alone b)REM alone c) both SEM AND REM d)neither SEM NOR REM The ____________ is the site of action potential initiation in most neurons because it has the lowest threshold. Which of the following activities is not carried out by every cell in the body? a)obtaining nutrient and o2 b)performing chemical reaction to acquire energy for the cell’s use c)eliminating waste d)controlling to a large extent exchange of materials between the cell and its external environment e)reproducing What is cytopathic effect? What are Merkel’s discs and Meisseners’s corpuscles? Mention the tiniest bones of the human body. Video Round Second Round Nano Robots What is the abbreviation of Nubots? Which is the main element used to construct nanorobots? What for MRN nanorobots used? Dyslexia In which film was this disorder picturised? (mock question) Who is the director of Taare Zameen Par? Name a few symptoms of this disorder. What are the types of Dyslexia? Paa Which genetic disorder is this film based upon? How is this disorder caused? Mention a few symptoms. Immune Response What is cyclosporine? How did thymus get its name? How many lymph nodes are present in the human body? Pronuclear Microinjection Which is the first genetically modified animal to be sold as pet? What do you mean by cisgenic plants? Name the leading U.S based multinational agricultural biotechnology corporation. Myocardial Infarction Why is aspirin given as first aid? Name any five risk factors for myocardial infarction. Which is good for health? LDL or HDL? Motility The movement of cells along a rigidity gradient is called _____________________. How does Eukaryotic flagella differ from that of prokaryotes? Name the protein present in bacterial flagella. Picture Revealing Third Round 6 2 3 1 9 5 8 4 7 BLOCK 1 He was born in Montclair, N.J. on May 23, 1925. BLOCK 2 American molecular biologist known for his work in genetics, artificial intelligence, and space exploration. BLOCK 3 In the year 1958, he was also elected to the National Academy of Sciences (USA). BLOCK 4 In 1978, he became the president of Rockefeller University. BLOCK 5 He began medical studies at Columbia's College of Physicians and Surgeons. BLOCK 6 In 1960s, he collaborated with Edward Feigenbaum in Stanford's computer science department to develop DENDRAL. BLOCK 7 He continues his research activities there in the field of interactions of gene functionality and mutagenesis in bacteria. BLOCK 8 He was just 33 years old when he won the 1958 Nobel Prize in Physiology or Medicine for discovering that bacteria can mate and exchange genes. BLOCK 9 He shared the prize with Edward L. Tatum and George Beadle who won for their work with genetics. 4 2 3 6 9 8 7 1 5 BLOCK 1 He discovered – in co-operation with Erwin Popper – the infectious character of Poliomyelitis and isolated the poliovirus. BLOCK 2 He was awarded Nobel Prize in Physiology or Medicine (1930). BLOCK 3 Major area of study- immunology BLOCK 4 In the field of bacteriology he and Clara Nigg succeeded in 1930-1932 in culturing Rickettsia prowazekii, the causative agent of typhus. BLOCK 5 Born in Vienna on June 14, 1868. (1868-06-14)Died on June 26, 1943 in New York City. BLOCK 6 Austrian-american biologist and pathologist. BLOCK 7 In 1909, he categorized the modern system for human bloods into A, B, AB, and O groups. BLOCK 8 He revealed new information regarding the immunology of syphilis and named the immunological factors haptens. BLOCK 9 With Alexander S. Wiener, he identified the Rh factor in 1937. 2 4 5 3 6 9 8 7 1 BLOCK1 Between 1988 and 1992, he was associated with the National Institutes of Health, helping to establish the Human Genome Project.   104 BLOCK 2 He is an American molecular biologist. BLOCK 3 He was awarded Nobel Prize for Physiology or Medicine (1962) and Copley Medal (1993). BLOCK 4 He also served as the advisor of Allen Institute for Brain Sciences. BLOCK 5 He was born on April 6, 1928. BLOCK 6 He authored the controversial book, ‘Avoid Boring People: Lessons from a Life in Science’, describes his academic colleagues as "dinosaurs," "deadbeats," "fossils," "has-beens," "mediocre," and "vapid. BLOCK 7 His famous quote, “Biology has atleast 50 more interesting years”. BLOCK 8 Between 1953 and 1955, he was at the California Institute of Technology as Senior Research Fellow in Biology. He collaborated with Alexander Rich in X-ray diffraction studies of RNA. BLOCK 9 He was the author of the textbook “The Molecular Biology of the Gene (1965)”. 1 2 4 5 3 6 9 8 7 113 BLOCK 1 The crater on the Moon is named after him.   BLOCK 2 He was awarded the Nobel Prize in Physiology or Medicine for his tuberculosis findings in 1905. BLOCK 3 He is considered as one of the founders of bacteriology along with Louis Pasteur. BLOCK 4 The son of a mining engineer, he astounded his parents at the age of five by telling them that he had, with the aid of the newspapers, taught himself to read. BLOCK 5 He was born on December 11,1843 and expired on May 27, 1910. BLOCK 6 He was a German physician. BLOCK 7 He became famous for isolating Bacillus anthracis (1877), the Tuberculosis bacillus (1882) and the Vibrio cholera (1883) BLOCK 8 He is known for his four assertions designed to establish a causal relationship between a causative microbe and a disease. BLOCK 9 He improved staining and purification techniques, and bacterial growth media, including agar plates . Rapid Fire Round Final Round SET 1 SET 1 SET 1 SET 2 SET 2 SET 2 SET 3 SET 3 SET 3 SET 4 SET 4 SET 4 Thank You
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